Closed system administration of Fluothane.

Fluothane(R) was administered in a closed system to 518 surgical patients. No morbidity or mortality was attributable to using Fluothane by this technique. Requisites for safe administration of Fluothane in a closed system include (1) an understanding of the basic concepts of closed systems, (2) a vaporizer outside of the breathing circuit which will accurately and dependably deliver precise amounts (in a range of 10 to 60 cc.) of oxygen saturated with Fluothane, and (3) a thermally stable vaporizer. If the demands for safe operation are met, Fluothane anesthesia with the closed system technique becomes the simplest, most economical and effective method for general anesthesia in adults.