FLETCHER G
Calif Med. 1961 Oct;95(4):232-6.
Fluothane(R) was administered in a closed system to 518 surgical patients. No morbidity or mortality was attributable to using Fluothane by this technique. Requisites for safe administration of Fluothane in a closed system include (1) an understanding of the basic concepts of closed systems, (2) a vaporizer outside of the breathing circuit which will accurately and dependably deliver precise amounts (in a range of 10 to 60 cc.) of oxygen saturated with Fluothane, and (3) a thermally stable vaporizer. If the demands for safe operation are met, Fluothane anesthesia with the closed system technique becomes the simplest, most economical and effective method for general anesthesia in adults.
在封闭系统中，向518名外科手术患者施用了氟烷。采用该技术使用氟烷未导致任何发病或死亡情况。在封闭系统中安全施用氟烷的必要条件包括：（1）理解封闭系统的基本概念；（2）呼吸回路外的蒸发器，其能准确可靠地输送精确量（10至60立方厘米范围内）的氟烷饱和氧气；（3）热稳定的蒸发器。如果满足安全操作要求，采用封闭系统技术的氟烷麻醉就成为成人全身麻醉最简单、最经济且最有效的方法。
