Bewley J S, Eltringham R J, Sanderson P
Department of Anaesthesia, Gloucester Royal Hospital, U.K.
Anaesth Intensive Care. 1998 Oct;26(5):558-62. doi: 10.1177/0310057X9802600513.
A study was undertaken to assess the performance of the Komesaroff vaporizer, placed within the circuit, in ventilated patients during maintenance of closed circuit anaesthesia with halothane or isoflurane. Following intravenous induction, anaesthesia was maintained by inhalation. This was achieved using a conventional vaporizer outside the circle for the first 10 minutes to manage the fast uptake phase. The fresh gas flow was then reduced to the basal oxygen requirement with the Komesaroff vaporizer within the circle maintaining inhalational anaesthesia. Complete isolation of the circuit was achieved by returning all anaesthetic gases to the circuit following analysis and using a bag-in-bottle ventilator. The Komesaroff vaporizer dial was positioned at between the first and second division and end-tidal volatile anaesthetic agent levels were measured. This study demonstrated that at dial positions 1 or 1.5 with either agent, the end-tidal volatile concentration plateaued at clinically acceptable levels. The Komesaroff vaporizer can therefore be used safely in ventilated patients to maintain closed circuit anaesthesia provided clinical observation and monitoring are meticulous.
开展了一项研究,以评估置于回路中的科梅萨罗夫蒸发器在使用氟烷或异氟烷进行闭合回路麻醉维持期间对通气患者的性能表现。静脉诱导后,通过吸入维持麻醉。在前10分钟使用回路外的传统蒸发器来处理快速摄取阶段,从而实现这一点。然后将新鲜气流减少至基础氧气需求量,由回路内的科梅萨罗夫蒸发器维持吸入麻醉。通过在分析后将所有麻醉气体返回回路并使用袋中瓶通气机,实现了回路的完全隔离。将科梅萨罗夫蒸发器刻度盘置于第一和第二刻度之间,并测量呼气末挥发性麻醉剂水平。这项研究表明,使用任何一种药剂时,在刻度盘位置1或1.5处,呼气末挥发性浓度稳定在临床可接受水平。因此,只要临床观察和监测细致入微,科梅萨罗夫蒸发器可安全用于通气患者以维持闭合回路麻醉。