Kula K, Thompson V, Kula T, Nelson S, Selvaggi R, Liao R
University of Maryland School of Dentistry.
J Esthet Dent. 1992 Jul-Aug;4(4):121-7. doi: 10.1111/j.1708-8240.1992.tb00678.x.
The purpose of this study was to determine by visual inspection and by scanning electron microscopy (SEM) whether commercially available, topical, acidulated phosphate fluoride (APF) and neutral sodium fluoride (NaF) agents cause surface roughening of five sealant materials: two unfilled resins, two filled resins, and one glass-ionomer material. In addition, the effect of treatment with 1.23% APF and sonification on weight of an unfilled and a filled sealant was compared to treatment with controls. Unfilled sealants exhibited no surface changes visually or on micrographs following any treatment. Filled sealants and the glass-ionomer sealant exhibited visually apparent changes depending on the treatment. SEM inspection of filled sealants with visually apparent changes showed loss of filler particles whereas the glass-ionomer sealant exhibited apparent destruction both of the matrix and the filler particle. No significant differences in weight were found between sonicated and unsonicated specimens. However, significant loss of weight was found with filled sealant specimens, but not unfilled sealant specimens, treated with 1.23% APF gel as compared with the specimens treated with water. The results of this in vitro study indicate that preventive therapies that combine use of topical fluorides and sealants may cause deterioration of filled sealants and glass-ionomer sealant material, but not unfilled sealants.
本研究的目的是通过目视检查和扫描电子显微镜（SEM）来确定市售的局部用酸化磷酸氟（APF）和中性氟化钠（NaF）制剂是否会导致五种封闭剂材料表面粗糙化，这五种材料分别为两种未填充树脂、两种填充树脂和一种玻璃离子材料。此外，还比较了用1.23% APF处理并超声处理对一种未填充封闭剂和一种填充封闭剂重量的影响与对照处理的效果。未填充封闭剂在任何处理后，在视觉上或显微照片上均未显示表面变化。填充封闭剂和玻璃离子封闭剂根据处理方式在视觉上呈现出明显变化。对视觉上有明显变化的填充封闭剂进行SEM检查显示填料颗粒损失，而玻璃离子封闭剂则显示出基质和填料颗粒均有明显破坏。超声处理和未超声处理的标本之间未发现重量有显著差异。然而，与用水处理的标本相比，用1.23% APF凝胶处理的填充封闭剂标本出现了显著的重量损失，但未填充封闭剂标本未出现。这项体外研究的结果表明，联合使用局部氟化物和封闭剂的预防性治疗可能会导致填充封闭剂和玻璃离子封闭剂材料劣化，但不会导致未填充封闭剂劣化。
