Selikowitz M
Tumbatin Developmental Clinic, Prince of Wales Children's Hospital, Sydney, Australia.
J Paediatr Child Health. 1992 Oct;28(5):383-6. doi: 10.1111/j.1440-1754.1992.tb02697.x.
A survey by parent questionnaire and interview was carried out to determine the frequency of health problems in 204 children with Down syndrome. Seventy-two children (35.3%) had a congenital heart defect. Refraction had been performed on 196 and 68 (34.6%) of these had a refractive error. A diagnosis of 'glue ear' had been made in 112 (54.9%) and in 12 (11%) of these permanent hearing loss was present. Significant ill-health over the previous 12 months consisted of cardiac failure (two children), more than three upper respiratory tract infections (24 children), bronchitis (eight children), pneumonia (two children) and asthma (seven children). A neck X-ray had been performed in 172 (84.3%) and had demonstrated the presence of atlanto-axial instability in 12 (7%) of these. One hundred and thirty-two (64.7%) of the children had been tested for hypothyroidism in the previous 18 months and this had been found in four (3%) of these children. The implications of these and other findings are discussed in relation to parental counselling and planning of routine health checks.
通过家长问卷和访谈进行了一项调查，以确定204名唐氏综合征患儿的健康问题发生频率。72名儿童（35.3%）患有先天性心脏病。对196名儿童进行了验光，其中68名（34.6%）有屈光不正。112名儿童（54.9%）被诊断为“胶耳”，其中12名（11%）存在永久性听力损失。在过去12个月中，严重健康问题包括心力衰竭（2名儿童）、超过三次上呼吸道感染（24名儿童）、支气管炎（8名儿童）、肺炎（2名儿童）和哮喘（7名儿童）。172名儿童（84.3%）进行了颈部X光检查，其中12名（7%）显示存在寰枢椎不稳定。在过去18个月中，132名儿童（64.7%）接受了甲状腺功能减退检测，其中4名（3%）儿童被发现患有该病。结合家长咨询和常规健康检查计划，对这些及其他发现的影响进行了讨论。
