GAREN A, ECHOLS H
J Bacteriol. 1962 Feb;83(2):297-300. doi: 10.1128/jb.83.2.297-300.1962.
Garen, A. (University of Pennsylvania, Philadelphia) and H. Echols. Properties of two regulating genes for alkaline phosphatase. J. Bacteriol. 83:297-300. 1962.-A constitutive mutation in one of the two regulating genes for alkaline phosphatase has two effects on the synthesis of the enzyme: repression of synthesis is blocked, and the cell's capacity to produce the enzyme is reduced. The behavior of this type of mutation has been studied in heterozygotes. The results suggest that the product of this regulating gene functions as an inducer as well as a repressor.
加伦,A.(宾夕法尼亚大学,费城)和H.埃科尔斯。碱性磷酸酶两个调节基因的特性。《细菌学杂志》83:297 - 300。1962年。——碱性磷酸酶两个调节基因之一的组成型突变对该酶的合成有两种影响:合成的阻遏被阻断,且细胞产生该酶的能力降低。已在杂合子中研究了这种类型突变的行为。结果表明,这个调节基因的产物既作为诱导剂又作为阻遏剂发挥作用。