两种碱性磷酸酶调节基因的特性
Properties of two regulating genes for alkaline phosphatase.
作者信息
GAREN A, ECHOLS H
出版信息
J Bacteriol. 1962 Feb;83(2):297-300. doi: 10.1128/jb.83.2.297-300.1962.
Abstract
Garen, A. (University of Pennsylvania, Philadelphia) and H. Echols. Properties of two regulating genes for alkaline phosphatase. J. Bacteriol. 83:297-300. 1962.-A constitutive mutation in one of the two regulating genes for alkaline phosphatase has two effects on the synthesis of the enzyme: repression of synthesis is blocked, and the cell's capacity to produce the enzyme is reduced. The behavior of this type of mutation has been studied in heterozygotes. The results suggest that the product of this regulating gene functions as an inducer as well as a repressor.
摘要
加伦，A.（宾夕法尼亚大学，费城）和H.埃科尔斯。碱性磷酸酶两个调节基因的特性。《细菌学杂志》83:297 - 300。1962年。——碱性磷酸酶两个调节基因之一的组成型突变对该酶的合成有两种影响：合成的阻遏被阻断，且细胞产生该酶的能力降低。已在杂合子中研究了这种类型突变的行为。结果表明，这个调节基因的产物既作为诱导剂又作为阻遏剂发挥作用。
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本文引用的文献
1
Genetic and chemical studies with alkaline phosphatase of E. coli.关于大肠杆菌碱性磷酸酶的遗传学和化学研究。
Brookhaven Symp Biol. 1959 Nov;12:76-85.
2
Influence of inorganic phosphate in the formation of phosphatases by Escherichia coli.无机磷酸盐对大肠杆菌中磷酸酶形成的影响。
Biochim Biophys Acta. 1960 Mar 11;38:460-9. doi: 10.1016/0006-3002(60)91281-6.
3
Genetic control of repression of alkaline phosphatase in E. coli.大肠杆菌中碱性磷酸酶阻遏的遗传控制
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