Poole J
NAACOGS Clin Issu Perinat Womens Health Nurs. 1992;3(3):461-8.
A major cause of maternal morbidity and mortality during pregnancy and the puerperium is thromboembolic disease. Pregnancy is a hypercoagulative state that predisposes the gravida to thrombus formation. Once a thrombus forms in the venous system of the lower extremities, it can travel to the pulmonary arterial bed, which can lead to hypoxemia or death. Maternal mortality associated with pulmonary embolism (PE) is approximately 14%. Most gravidas who have PE during or after pregnancy have no history of thromboembolic disease at the time of insult.
孕期及产褥期孕产妇发病和死亡的一个主要原因是血栓栓塞性疾病。妊娠是一种高凝状态，使孕妇易形成血栓。一旦血栓在下肢静脉系统形成，它可能会转移至肺动脉床，从而导致低氧血症或死亡。与肺栓塞（PE）相关的孕产妇死亡率约为14%。大多数在孕期或产后发生肺栓塞的孕妇在发病时并无血栓栓塞性疾病史。
