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糖尿病酮症酸中毒

Diabetic ketoacidosis.

作者信息

Mandeville L K

出版信息

NAACOGS Clin Issu Perinat Womens Health Nurs. 1992;3(3):514-20.

PMID:1389807
Abstract

Diabetic ketoacidosis (DKA) is a form of decompensated diabetes. When it occurs during pregnancy, it may lead to maternal and fetal morbidity and mortality. DKA is defined by accelerated gluconeogenesis and ketogenesis and occurs most often in the presence of one of four predisposing factors: insulin deficiency (absolute or relative); excess counter regulatory hormones; fasting; and dehydration. Infection is a common catalyst. Once the disorder is diagnosed, intensive obstetrical nursing care is required. The principles of management include rehydration, insulin therapy, electrolyte replacement, and identification and treatment of the underlying cause. A plan for assessment of the pregnant patient with diabetes and in DKA and treatment guidelines are presented.

摘要

糖尿病酮症酸中毒(DKA)是一种失代偿性糖尿病。当它发生在孕期时,可能导致母婴发病和死亡。DKA的定义是糖异生和酮体生成加速,最常发生于以下四个诱发因素之一的情况下:胰岛素缺乏(绝对或相对);反调节激素过多;禁食;以及脱水。感染是常见的促发因素。一旦诊断出该病症,就需要强化产科护理。治疗原则包括补液、胰岛素治疗、电解质补充以及识别和治疗潜在病因。本文介绍了对患有糖尿病且发生DKA的孕妇进行评估的计划和治疗指南。

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