Maynard J A, Cooper R R, Ionaescu V V
Virchows Arch A Pathol Anat Histol. 1977 Feb 18;373(1):1-13. doi: 10.1007/BF00432464.
Ultrastructure features of muscle spindles from two patients with myotonic dystrophy are described. Intrafusal muscle fibers exhibit extensive splitting with nuclear bag fibers affected more so than nuclear chain fibers. No sensory endings are present on nuclear chain fibers nor on one nuclear bag fiber throughout the equatorial and myotube regions. Small motor end plates are evident on various segments of split intrafusal fibers in the polar region and some of these extend into the myotube region. Satellite cells are numerous on both nuclear bag and nuclear chain fibers. These frequently occupy the cleft space between segments of split intrafusal fibers. The myotonic dystrophy muscle spindle ultrastructure features seem to closely resemble the appearance of developing mammalian muscle spindles as illustrated with opossum fetal tissue.
描述了两名强直性肌营养不良患者肌梭的超微结构特征。梭内肌纤维出现广泛分裂，核袋纤维比核链纤维受影响更严重。在赤道区和肌管区的核链纤维以及一根核袋纤维上均未发现感觉末梢。在极区，分裂的梭内纤维的不同节段可见小运动终板，其中一些延伸至肌管区。核袋纤维和核链纤维上均有大量卫星细胞。这些卫星细胞经常占据分裂的梭内纤维节段之间的裂隙空间。强直性肌营养不良肌梭的超微结构特征似乎与发育中的哺乳动物肌梭的外观非常相似，负鼠胎儿组织的情况就是例证。
