Cinbis M, Aysun S
Department of Pediatric Neurology, Hacettepe Children's Hospital, Hacettepe University, Faculty of Medicine, Turkey.
Br J Ophthalmol. 1992 May;76(5):316. doi: 10.1136/bjo.76.5.316.
We present a patient with serologically confirmed Epstein-Barr virus (EBV) infection who had illusions of size, shape, and colour of objects but none of the typical symptoms and signs peculiar to infectious mononucleosis (IM) except sore throat which developed 2 weeks after the initial visual disturbances. The bizarre feelings about the images of body and objects are called the 'Alice in Wonderland syndrome' due to the similarity with Alice's dreams. The same symptomatology including visual metamorphosia is defined in patients with migraine, epilepsy, intoxication due to hallucinogenic drugs, schizophrenia, hyperpyrexia, and cerebral lesions. Alice in Wonderland syndrome has also been reported in the course of IM.
我们报告一例血清学确诊为爱泼斯坦-巴尔病毒(EBV)感染的患者,该患者出现物体大小、形状和颜色的幻觉,但除了在最初视觉障碍出现2周后出现的喉咙痛外,没有传染性单核细胞增多症(IM)特有的典型症状和体征。由于与爱丽丝的梦境相似,对身体和物体形象的奇异感觉被称为“爱丽丝梦游仙境综合征”。偏头痛、癫痫、致幻药物中毒、精神分裂症、高热和脑损伤患者也有包括视物变形症在内的相同症状表现。在IM病程中也有爱丽丝梦游仙境综合征的报道。