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职业性呼吸道暴露中的甲醛致敏作用

[Formaldehyde sensitization in occupational respiratory exposure].

作者信息

Wallenstein V G, Rebohle E

出版信息

Allerg Immunol (Leipz). 1976;22(3):287-90.

PMID:139093
Abstract

The determination in a total of 180 workmen regularly exposed to varying breathing zone levels of for-maldehyde of an index of sensitization as low as 12.2% may be interpreted to mean that formaldehyde exerts only a rather weak effect on the respiratory tract. It was not possible for allergoses to be clinically established even if consideration was given to technical difficulties encountered in the use of provocative tests conducted for diagnostic purposes. Rather, the conditions of exposure and the results of tests may be regarded as suggestion that the nonspecific symptomatology was produced by irritation. What is also of considerable importance in this connection is that extremely wide difference in individual sensitivity were observed.

摘要

在总共180名经常暴露于不同呼吸带甲醛浓度的工人中,致敏指数低至12.2%,这可能意味着甲醛对呼吸道的影响相当微弱。即使考虑到用于诊断目的的激发试验在技术上存在困难,也无法在临床上确诊过敏症。相反,暴露条件和试验结果可被视为非特异性症状是由刺激引起的迹象。在这方面同样相当重要的是,观察到个体敏感性存在极大差异。

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