Chikos P M, Figley M M, Fisher L
AJR Am J Roentgenol. 1977 Mar;128(3):367-73. doi: 10.2214/ajr.128.3.367.
In 76 adult males quantitative angiographic measurements of left ventricular size were compared to 12 plain chest film measurements of heart size and shape. Of the 18 normal cases, only Rigler's B measurement correlated with left ventricular volume (r = .64). However, this correlation was not statistically significant. Of the 58 patients with isolated aortic valve disease, 19 had increased left ventricular mass (hypertrophy) and 39 had both increased left ventricular end-diastolic volume and mass (hypertrophy and dilatation). In the hypertrophy group, plain film heart volume was the most sensitive detector of an enlarged left ventricle (21% false negative rate) and correlated with left ventricular end-diastolic volume (r = .62). Using stepwise discriminant analysis, the combination of heart volume, leftness of the heart, apex position, and roundness of the left ventricle decreased the false negative rate to 5%. In the hypertrophy and dilatation group, plain film heart volume had the highest correlation with left ventricular volume and mass (r = .66) and a false negative rate of 8%. No single variable or combination of variables could usefully discriminate between the hypertrophy and hypertrophy and dilatation groups. These data support the conclusion that plain film heart volume is the best single measurement for detecting left ventricular enlargement.
对76名成年男性进行了左心室大小的定量血管造影测量，并与12次胸部平片测量的心脏大小和形状进行了比较。在18例正常病例中，只有里格勒B测量值与左心室容积相关（r = 0.64）。然而，这种相关性在统计学上并不显著。在58例单纯主动脉瓣疾病患者中，19例左心室质量增加（肥厚），39例左心室舒张末期容积和质量均增加（肥厚和扩张）。在肥厚组中，平片心脏容积是左心室扩大最敏感的检测指标（假阴性率为21%），且与左心室舒张末期容积相关（r = 0.62）。采用逐步判别分析，心脏容积、心脏偏左程度、心尖位置和左心室圆度的组合可将假阴性率降至5%。在肥厚和扩张组中，平片心脏容积与左心室容积和质量的相关性最高（r = 0.66），假阴性率为8%。没有单一变量或变量组合能够有效地区分肥厚组与肥厚和扩张组。这些数据支持这样的结论，即平片心脏容积是检测左心室扩大的最佳单一测量指标。
