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[左心室肥厚。缺血性心脏病心室造影结果的相关性]

[Left ventricular hypertrophy. Correlation of ventriculographic findings in ischemic cardiopathy].

作者信息

Gil Moreno M, Cisneros F, Martínez-Ríos M A, Grande F

出版信息

Arch Inst Cardiol Mex. 1980 Sep-Oct;50(5):545-51.

PMID:6451206
Abstract

In order to analyze the angiographic characteristics associated with left ventricular hypertrophy in patients with coronary insufficiency, the left ventriculography was used to calculate the ventricular volumes, the ejection fraction (EF) and the ventricular mass (LVM) in 31 patients with clinical diagnosis of ischemic heart disease. Patients were divided into three groups: A) Those with normal coronaries and (EF), B) Those with coronary lesion and EF greater than 50% and C) Those with coronary lesions and EF less than 50%. The following results were obtained for the telediastolic volume (ml/m2), the EF (%) and the LUM (g/m2): Group A = 85 +/- 19, 73 +/- 7 and 41 +/- 13. Group B = 102 +/- 25, 61 +/- 8 and 50 +/- 9. Group C = 154 +/- 27, 39 /+- 7 and 74 +/- 17 respectively. Comparing the FEV with the LVM in the patients studied, a negative correlation was found with an r index of -0.7894 (p less than or equal to 0.001). The correlation index for the diastolic volume and the LVM was r = 0.6806; and -0.6991 for the EF and the telediastolic volume. These findings suggest that hemodinamic changes, especially an increase in the ventricular volume and subsequently in the tension of the ventricular wall, act as a stimulus in initiating a metabolic chain leading to ventricular hypertrophy. This process is compensatory in the initial phases of the disease (groups A and B) but insufficient in the advanced stage (group C).

摘要

为分析冠心病患者左心室肥厚相关的血管造影特征,采用左心室造影术计算31例临床诊断为缺血性心脏病患者的心室容积、射血分数(EF)和心室质量(LVM)。患者分为三组:A组,冠状动脉正常且EF正常;B组,有冠状动脉病变且EF大于50%;C组,有冠状动脉病变且EF小于50%。得到以下舒张末期容积(ml/m²)、EF(%)和LUM(g/m²)结果:A组 = 85±19、73±7和41±13;B组 = 102±25、61±8和50±9;C组分别为154±27、39±7和74±17。在所研究患者中比较FEV与LVM,发现呈负相关,r指数为-0.7894(p≤0.001)。舒张末期容积与LVM的相关指数为r = 0.6806;EF与舒张末期容积的相关指数为-0.6991。这些发现提示血液动力学改变,尤其是心室容积增加及随后心室壁张力增加,在启动导致心室肥厚的代谢链中起刺激作用。此过程在疾病初期(A组和B组)具有代偿性,但在晚期(C组)则不足。

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