Hamanaka S, Hamanaka Y, Otsuka F
Department of Dermatology, Yamaguchi Rosai Hospital, Onoda, Japan.
Dermatology. 1992;184(3):210-2. doi: 10.1159/000247544.
We report a case of primary irritant contact dermatitis caused by an organostannic insecticide, tributyl tin phthalate, which has been thought to be stable and safe. A factory worker has been in contact with raw tributyl tin phthalate on one leg. Soon after taking a hot-water bath, he developed severely painful erythema on this leg. Patch tests and chemical analysis revealed that hot water hydrolyzed tributyl tin phthalate and produced concentrated phthalic acid. Since phthalic acid, a weak acid, was then concentrated, an acute irritant reaction appeared in this patient.
我们报告一例由有机锡杀虫剂邻苯二甲酸三丁酯引起的原发性刺激性接触性皮炎，该杀虫剂一直被认为是稳定且安全的。一名工厂工人的一条腿接触了邻苯二甲酸三丁酯原液。在洗热水澡后不久，他的这条腿出现了剧痛性红斑。斑贴试验和化学分析表明，热水使邻苯二甲酸三丁酯水解并产生了浓缩的邻苯二甲酸。由于邻苯二甲酸这种弱酸随后被浓缩，该患者出现了急性刺激性反应。
