Lewis P G, Emmett E A
Division of Occupational Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21211.
Contact Dermatitis. 1987 Sep;17(3):129-32. doi: 10.1111/j.1600-0536.1987.tb02689.x.
A shipwright developed a delayed bullous irritant dermatitis from contact with a bis-tri-butyl tin oxide (TBTO) containing antifouling paint. He subsequently developed sensitization to 4-chloro-m-cresol, a constituent of a steroid cream. No cross sensitivity to 4-chloro-3,5 xylenol was seen. Low concentrations of 4-chloro-m-cresol in pet. may elicit a true positive reaction. TBTO is a strong irritant which will produce delayed bullous reactions in industrial use and on patch testing at 0.1% aqueous.
一名造船工人因接触含双三丁基氧化锡(TBTO)的防污漆而患上迟发性大疱性刺激性皮炎。他随后对一种类固醇乳膏的成分4-氯间甲酚产生了过敏反应。未发现对4-氯-3,5-二甲苯酚有交叉过敏反应。宠物身上低浓度的4-氯间甲酚可能会引发真正的阳性反应。TBTO是一种强刺激物,在工业使用中以及在0.1%水溶液的斑贴试验中会产生迟发性大疱反应。