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[神经源性尿道。尿道造影及病理生理方面]

[Neurogenic urethra. Urethrogram and pathophysiological aspects].

作者信息

Madersbacher H

出版信息

Fortschr Med. 1977 Feb 17;95(7):421-5.

PMID:139353
Abstract

In the analysis of neurogenic urinary voiding disturbances, too much attention has been paid to the bladder, too little to the muscular tubing of the posterior urethra and to the pelvic floor. Contrast radiography of the urethra in injection and micturition, combined with urodynamic investigations, seemed suitable for comprehension of neurogenic functional disturbances of the posterior urethra and the pelvic floor. A cross section of 143 predominantly traumatic patients and 69 patients with myelomeningocele were investigated radiologically. In addition, in a number of patients urinary flow was determined by uroflowmetry and micturition studies with simultaneous recording of intravesical and intrarectal pressure, of the EMG-activity of the pelvic floor and urinary flow were performed by a special method. The radiologic section shows that the urinary picture of various neurogenic bladder types are characterized by specific changes in form of the posterior urethra. With the help of systematic investigations of a number of cases it was demonstrated that in automatic bladder the roentgen contour of the urethra changes with duration of illness and that primarily secondary, morphologic changes--recognizable at the same time from the increasing number of radiologically demonstrable changes of the prostate and the seminal vesicles--are responsible. Simultaneously a typical deformation of the posterior urethra in passive urinary voiding is described, and attention directed to the fact that the urinary pictures of children with neurogenic impaired urethra sometimes cannot be distinguished from those with urethral values. Urinary flow measurements show that the flow rates from a cross section of patients with lesions of the upper and lower neurons are significantly lower in comparison to normals. With the help of combined urodynamic investigations it was demonstrated that a functional obstruction was present in the neurogenic bladder at the level of spastic and of paretic pelvic floors. It was proved that the roentgenologically visible deformation of the posterior urethra plays a quite decisive role in neurogenically disturbed urinary voiding. It is the main reason why, despite sufficient bladder pressure values, urinary voiding remains unsatisfactory and urinary performance low. Hence the therapeutic consequence follows: an improvement in urinary performance in neurogenic bladder is generally only possible through a decrease in the expulsion resistance. Various operative procedures for the release of bladder outlet obstruction and their uses are discussed.

摘要

在对神经源性排尿障碍的分析中,人们对膀胱关注过多,而对后尿道的肌性管道和盆底关注过少。尿道注射造影和排尿造影与尿动力学检查相结合,似乎有助于理解后尿道和盆底的神经源性功能障碍。对143例主要为创伤性患者和69例脊髓脊膜膨出患者进行了放射学检查。此外,对一些患者通过尿流率测定来确定尿流情况,并采用特殊方法在排尿研究中同时记录膀胱内压、直肠内压、盆底肌电图活动和尿流情况。放射学检查显示,各种神经源性膀胱类型的尿路影像以后尿道形态的特定改变为特征。通过对一系列病例的系统研究表明,在自主性膀胱中,尿道的X线轮廓随病程而变化,主要是继发性形态学改变——同时可从前列腺和精囊越来越多的放射学可见改变中识别出来——起了作用。同时描述了被动排尿时后尿道的典型变形,并指出神经源性尿道受损儿童的尿路影像有时无法与尿道瓣膜病患者的影像区分开来。尿流测量结果显示,与正常人相比,上、下神经元损伤患者的尿流率明显较低。通过联合尿动力学检查表明,神经源性膀胱在痉挛性和弛缓性盆底水平存在功能性梗阻。已证实后尿道的X线可见变形在神经源性排尿障碍中起相当决定性的作用。这就是为什么尽管膀胱压力值足够,但排尿仍不令人满意且排尿效率低下的主要原因。因此得出治疗结论:神经源性膀胱排尿效率的提高通常只能通过降低排尿阻力来实现。文中讨论了各种解除膀胱出口梗阻的手术方法及其应用。

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Fortschr Med. 1977 Feb 17;95(7):421-5.
2
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