Jonas U
Z Urol Nephrol. 1979 Oct;72(10):745-60.
The lower urinary tract undergoes a threefold nervous regulation. The normal miction is characterized by the fact that in the contraction of the detrusor an active reflected relaxation of the urethral occlusive mechanism develops. This could be proved experimentally at an animal model. On principle the miction could be disturbed on four ways: Incontinence, obstruction, neurogenic bladder, instability of the bladder. The most important differential diagnosis in the incontenencies is the differentiation between stress incontinence and urge incontinence, this differentiation is urodynamically significantly possible. In an obstructive disturbance of the miction one differs the mechanically fixed obstructions from the functional disturbances. For the two possibilities clinical instances are cited: Urethral valve--spastic neck of the bladder--detrusor-sphincter-dyssynergy. Neurogenic disturbances of micturition may be diagnosed only to the extent that their effect is objectiviable at the aim organ (urinary bladder and urethra). Non-neurogenic disturbances, however, show identical pictures, so that one may speak of a disturbance of micturition which corresponds to a certain type of neurogenic lesion. Every kind of disturbance of micturition needs an exact diagnostics. Urodynamic examinations are in every case necessary for the differential diagnosis of the individual disturbance.
下尿路接受三重神经调节。正常排尿的特点是,在逼尿肌收缩时,尿道阻塞机制会出现主动反射性松弛。这一点在动物模型上已得到实验证明。原则上,排尿可通过四种方式受到干扰:尿失禁、梗阻、神经源性膀胱、膀胱不稳定。尿失禁最重要的鉴别诊断是压力性尿失禁和急迫性尿失禁之间的区分,这种区分在尿动力学上是可行的。在排尿梗阻性障碍中,要区分机械性固定梗阻和功能性障碍。针对这两种情况列举了临床实例:尿道瓣膜——膀胱痉挛性颈部——逼尿肌-括约肌协同失调。排尿的神经源性障碍只有在其对靶器官(膀胱和尿道)的影响能够客观化的程度上才能被诊断出来。然而,非神经源性障碍表现出相同的症状,因此可以说存在一种与某种类型神经源性病变相对应的排尿障碍。每种排尿障碍都需要精确的诊断。尿动力学检查对于个体障碍的鉴别诊断在任何情况下都是必要的。