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性别二态性的代谢评估。V. 睾酮对体外培养的小鼠颌下腺细胞磷酸果糖激酶的作用

Metabolic evaluation of sexual dimorphism. V. Action of testosterone on the phosphofructokinase of mice submaxillary gland cells in vitro.

作者信息

Floridi A, Marcante M L, Benassi M

出版信息

Ital J Biochem. 1976 Sep-Oct;25(5):357-66.

PMID:139384
Abstract
  1. The kinetics of phosphofructokinase and growth rate of submaxillary gland cells of C3H mice of both sexes in presence and in absence of testosterone have been studied. 2) Both enzymes show sigmoidal kinetics, with Hill's coefficient higher for the females. 3) The maximal activity is remarkably more elevated for the males. 4) The testosterone modifies the growth rate and the kinetic properties of the phosphofructokinase and these modifications depend on the sex.
摘要
  1. 研究了在有和没有睾酮的情况下，C3H 雌雄小鼠颌下腺细胞中磷酸果糖激酶的动力学和生长速率。2) 两种酶均呈现 S 形动力学，雌性的希尔系数更高。3) 雄性的最大活性显著更高。4) 睾酮改变了磷酸果糖激酶的生长速率和动力学特性，且这些改变取决于性别。

相似文献

1
Metabolic evaluation of sexual dimorphism. V. Action of testosterone on the phosphofructokinase of mice submaxillary gland cells in vitro.性别二态性的代谢评估。V. 睾酮对体外培养的小鼠颌下腺细胞磷酸果糖激酶的作用
Ital J Biochem. 1976 Sep-Oct;25(5):357-66.
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Metabolic evaluation of sexual dimorphism. 3. Effect of epinephrine, dibutyryl-cyclic AMP and cyclic-AMP on the energy metabolism of mice submaxillary glands.
Ital J Biochem. 1972 Jan-Apr;21(1):23-33.
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Sexual dimorphism of SDS peptide patterns from the submaxillary glands of mice.小鼠颌下腺SDS肽谱的两性差异
J Exp Zool. 1981 Dec;218(3):447-53. doi: 10.1002/jez.1402180317.
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[Effect of testosterone on the submaxillary gland in mice].
Ann Ist Super Sanita. 1966;2(2):356-62.
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Age related increase and androgen dependence of enzymes in the mouse submaxillary gland.小鼠颌下腺中酶的年龄相关性增加及雄激素依赖性
J Physiol. 1972 Sep;225(2):26P-27P.
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Glycosidases in the submaxillary gland of the mouse: sexual dimorphism and the effects of testosterone.
Int J Biochem. 1978;9(4):235-8. doi: 10.1016/0020-711x(78)90004-6.
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Sex difference in glucose-6-phosphate dehydrogenase activity in the submandibular gland of mice.
Biochim Biophys Acta. 1974 Aug 7;362(1):110-20. doi: 10.1016/0304-4165(74)90032-4.
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[Extraction of messenger RNA from the submaxillary gland of the mouse treated with testosterone].
Boll Mal Orecch Gola Naso. 1970;88(2):152-7.
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[Sexual dimorphism in rat submaxillary gland].[大鼠颌下腺的两性异形]
Acta Odontol Latinoam. 1990;5(1):63-9.
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Sexual difference in properties of 5 alpha-reductase in microsome of rat submandibular glands.大鼠下颌下腺微粒体中5α-还原酶性质的性别差异。
Biochem Int. 1987 Oct;15(4):761-8.

引用本文的文献

1
Anabolic-androgenic steroids: In cell culture.合成代谢雄激素类固醇：在细胞培养中。
In Vitro Cell Dev Biol Anim. 1993 Jun;29(6):433-8. doi: 10.1007/BF02639373.
2
On the in vitro behaviour of mouse submaxillary gland cells. II. Metabolic differences between male and female C3H mice.关于小鼠下颌下腺细胞的体外行为。II. C3H 雄性和雌性小鼠之间的代谢差异。
Experientia. 1977 Nov 15;33(11):1420-2. doi: 10.1007/BF01918779.