利用噬菌体降解和反向检测核磁共振实验对肺炎克雷伯菌K15荚膜多糖结构进行重新研究。
Re-investigation of the structure of the capsular polysaccharide of Klebsiella K15 using bacteriophage degradation and inverse-detected NMR experiments.
作者信息
Parolis H, Parolis L A, Whittaker D V
机构信息
School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.
出版信息
Carbohydr Res. 1992 Jul 2;231:93-103. doi: 10.1016/0008-6215(92)84011-g.
PMID:1394332
Abstract
The structure of the capsular polysaccharide from Klebsiella K15 has been re-investigated, principally by 1D and 2D 1H- and 13C-NMR spectroscopy of the oligosaccharide-alditol obtained by depolymerisation of the polysaccharide with a viral-borne endoglycanase followed by borohydride reduction of the isolated repeating oligosaccharide. The capsular polysaccharide was shown to have the repeating unit: [Formula: see text]
摘要
肺炎克雷伯菌K15荚膜多糖的结构已被重新研究，主要通过对用病毒携带的内切糖苷酶使多糖解聚，然后对分离出的重复寡糖进行硼氢化还原得到的寡糖糖醇进行一维和二维¹H-和¹³C-核磁共振光谱分析。结果表明，该荚膜多糖具有重复单元：[化学式：见原文]
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