Pasmans H L, Go P M, Gouma D J, Heidendal G A, van Engelshoven J M, van Kroonenburgh M J
Department of Diagnostic Radiology, University Hospital Maastricht, The Netherlands.
Clin Nucl Med. 1992 Sep;17(9):697-700. doi: 10.1097/00003072-199209000-00001.
To assess the role of Tc-99m IDA cholescintigraphy in diagnosing bile leakage and bile obstruction after laparoscopic cholecystectomy, 51 studies were performed in 51 patients on the first postoperative day. Two different radioactive bile acid analogs were used, Tc-99m HIDA and Tc-99m trimethylbromo IDA. Scintigraphic findings were correlated with the clinical conditions. Results of seven out of 51 cholescintigrams were abnormal, showing accumulations of activity in the right paracolic gutter. Of these seven patients, only three had clinical symptoms consisting of more than normal postoperative abdominal pain and peritoneal irritation. The other four patients had minimal abnormal accumulation in the right paracolic gutter and showed no clinical signs postoperatively. Complete common bile duct obstruction or other bile duct-related complications, except for bile leakage, were not observed. Cholescintigraphy is feasible for the early detection of bile leakage and bile flow obstruction after laparoscopic cholecystectomy in patients with increased postoperative abdominal discomfort.
为评估锝-99m亚氨基二乙酸(Tc-99m IDA)肝胆闪烁显像在诊断腹腔镜胆囊切除术后胆漏和胆管梗阻中的作用,对51例患者在术后第1天进行了51项研究。使用了两种不同的放射性胆汁酸类似物,即锝-99m 二乙基乙酰苯胺亚氨基二乙酸(Tc-99m HIDA)和锝-99m 三甲基溴亚氨基二乙酸(Tc-99m trimethylbromo IDA)。闪烁显像结果与临床情况相关。51例肝胆闪烁显像中有7例结果异常,显示右侧结肠旁沟有放射性聚集。在这7例患者中,只有3例有临床症状,表现为术后腹痛超过正常程度和腹膜刺激征。另外4例患者右侧结肠旁沟有轻微异常聚集,术后未出现临床体征。未观察到除胆漏外的胆总管完全梗阻或其他胆管相关并发症。对于术后腹部不适增加的患者,肝胆闪烁显像对于腹腔镜胆囊切除术后胆漏和胆汁流动梗阻的早期检测是可行的。