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8-羟基喹啉盐与芳香族羟基羧酸形成的金属螯合物的抗菌活性

Antimicrobial activity of metal chelates of salts of 8-quinolinols with aromatic hydroxycarboxylic acids.

作者信息

GERSHON H, NICKERSON W J

出版信息

Appl Microbiol. 1962 Nov;10(6):556-60. doi: 10.1128/am.10.6.556-560.1962.

Abstract

Thirty-seven metal chelate complexes of salts of 8-quinolinols with aromatic hydroxycarboxylic acids were screened by the disc-plate method against strains of five bacteria and five fungi. The copper (II) chelates of 8-quinolinolium salicylate and 8-quinolinolium-3'-hydroxy-2'-naphthoate showed outstanding antifungal and good antibacterial properties and appear to be potentially more economical than copper (II) 8-quinolinolate.

摘要

采用滤纸片法,对37种8-喹啉醇盐与芳香族羟基羧酸形成的金属螯合物针对5种细菌菌株和5种真菌菌株进行了筛选。水杨酸8-喹啉醇铜(II)螯合物和3'-羟基-2'-萘酸8-喹啉醇铜(II)螯合物表现出优异的抗真菌性能和良好的抗菌性能,而且似乎比8-羟基喹啉铜(II)更具成本效益。

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Antimicrobial activity of metal chelates of salts of 8-quinolinols with aromatic hydroxycarboxylic acids.
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