Hockman C H, Gossman M D, Liddell N E, Renehan W E
Division of Basic Medical Sciences, Mercer University School of Medicine, Macon, Georgia 31207.
Exp Neurol. 1992 Sep;117(3):307-12. doi: 10.1016/0014-4886(92)90140-l.
In preliminary experiments with dogs and cats, unilateral paralysis of the orbicularis oculi muscle group was produced by a section of the seventh nerve that included the posterior auricular branch. Either one of two procedures was then employed in attempts to reinnervate the paralyzed eyelid. In one group of animals, a neuromuscular pedicle was employed and in another, a contralateral orbicularis innervated muscle flap was used. Both methods restored synchronous, reflex blinking to the denervated eyelid. Of the two procedures, neurotization appears to offer the greater promise because the use of a neuromuscular pedicle requires an expendable nerve that is functional, and no such suitable substitute is available in humans.
在对狗和猫进行的初步实验中，通过切断包含耳后支的第七神经，造成眼轮匝肌组单侧麻痹。然后采用两种方法之一试图使麻痹的眼睑重新获得神经支配。在一组动物中，使用了神经肌肉蒂，而在另一组中，使用了由对侧眼轮匝肌支配的肌瓣。两种方法均使去神经支配的眼睑恢复了同步的反射性眨眼。在这两种方法中，神经移植似乎更具前景，因为使用神经肌肉蒂需要一条功能正常的可牺牲神经，而在人类中没有这样合适的替代神经。
