Salerno G M, Bleicher J N, Stromberg B V, Cheng S C
Division of Plastic and Reconstructive Surgery, Creighton University School of Medicine, Omaha, NE 68131.
Ann Plast Surg. 1990 Jan;24(1):24-31. doi: 10.1097/00000637-199001000-00005.
This study investigated the electrophysiology of the denervated orbicularis oculi muscle and its clinical application. Orbicularis oculi muscle denervation was achieved by complete transection of the seventh nerve in ten dogs. The parameters studied were the electrical requirements needed to cause a minimal perceptible contraction (twitch) and a complete eyelid closure (blink). Twitch and blink curves were generated. The findings are summarized as follows: (1) Minimum intensities for direct twitch of denervated orbicularis oculi muscle were significantly lower than intensities of normal orbicularis oculi muscle twitch (p less than 0.01) when long stimulus duration (5 to 400 ms) was used. (2) Minimum intensities for direct blink of denervated orbicularis oculi muscle were not significantly different from stimulus intensities for blink of normal orbicularis oculi muscle if long stimulus duration (5 to 400 ms) was used. Twitch and blink curves could be used to clinically follow the orbicularis oculi muscle movement return after operations performed in patients affected by lagophthalmos.
本研究调查了失神经支配的眼轮匝肌的电生理学及其临床应用。通过完全切断十只犬的第七神经来实现眼轮匝肌失神经支配。所研究的参数是引起最小可感知收缩（抽搐）和完全眼睑闭合（眨眼）所需的电刺激条件。生成了抽搐和眨眼曲线。研究结果总结如下：（1）当使用长刺激持续时间（5至400毫秒）时，失神经支配的眼轮匝肌直接抽搐的最小强度显著低于正常眼轮匝肌抽搐的强度（p小于0.01）。（2）如果使用长刺激持续时间（5至400毫秒），失神经支配的眼轮匝肌直接眨眼的最小强度与正常眼轮匝肌眨眼的刺激强度无显著差异。抽搐和眨眼曲线可用于临床追踪睑裂闭合不全患者手术后眼轮匝肌运动的恢复情况。
