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1
Role of free fatty acids in forearm metabolism in man, quantitated by use of insulin.游离脂肪酸在人体前臂代谢中的作用，通过胰岛素进行定量研究。
J Clin Invest. 1962 Dec;41(12):2191-7. doi: 10.1172/JCI104678.
2
EFFECT OF VERY SMALL CONCENTRATIONS OF INSULIN ON FOREARM METABOLISM. PERSISTENCE OF ITS ACTION ON POTASSIUM AND FREE FATTY ACIDS WITHOUT ITS EFFECT ON GLUCOSE.极低浓度胰岛素对前臂代谢的影响。其对钾和游离脂肪酸的作用持续存在，而对葡萄糖无作用。
J Clin Invest. 1964 May;43(5):950-62. doi: 10.1172/JCI104981.
3
Heterogeneity of forearm metabolism with special reference to free fatty acids.前臂代谢的异质性，特别涉及游离脂肪酸。
J Clin Invest. 1962 Jan;41(1):116-25. doi: 10.1172/JCI104453.
4
Role of insulin and free fatty acid (FFA) availability on regional FFA kinetics in the human forearm.胰岛素和游离脂肪酸（FFA）的可利用性对人体前臂局部FFA动力学的作用。
J Clin Endocrinol Metab. 1994 Sep;79(3):879-82. doi: 10.1210/jcem.79.3.8077375.
5
Quantitation of forearm glucose and free fatty acid (FFA) disposal in normal subjects and type II diabetic patients: evidence against an essential role for FFA in the pathogenesis of insulin resistance.正常受试者和II型糖尿病患者前臂葡萄糖和游离脂肪酸（FFA）代谢的定量分析：反对FFA在胰岛素抵抗发病机制中起关键作用的证据。
J Clin Endocrinol Metab. 1988 Nov;67(5):893-8. doi: 10.1210/jcem-67-5-893.
6
SERIAL STUDIES ON THE METABOLISM OF HUMAN ADIPOSE TISSUE. II. EFFECTS OF CALORIC RESTRICTION AND REFEEDING ON LIPOGENESIS, AND THE UPTAKE AND RELEASE OF FREE FATTY ACIDS IN OBESE AND NONOBESE INDIVIDUALS.人体脂肪组织代谢的系列研究。II. 热量限制和再喂养对肥胖及非肥胖个体脂肪生成以及游离脂肪酸摄取与释放的影响。
J Clin Invest. 1964 Sep;43(9):1793-804. doi: 10.1172/JCI105053.
7
Effect of glycemia and nonesterified fatty acids on forearm glucose uptake in normal humans.血糖和非酯化脂肪酸对正常人体内前臂葡萄糖摄取的影响。
Am J Physiol. 1991 Sep;261(3 Pt 1):E304-11. doi: 10.1152/ajpendo.1991.261.3.E304.
8
Forearm metabolism in obesity and its response to intra-arterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism.肥胖状态下前臂的新陈代谢及其对动脉内胰岛素的反应。胰岛素抵抗的特征及适应性高胰岛素血症的证据。
J Clin Invest. 1962 Dec;41(12):2173-81. doi: 10.1172/JCI104676.
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Amino acid balance across tissues of the forearm in postabsorptive man. Effects of insulin at two dose levels.空腹状态下人体前臂各组织间的氨基酸平衡。两种剂量胰岛素的作用。
J Clin Invest. 1969 Dec;48(12):2273-82. doi: 10.1172/JCI106193.
10
Effect of fasting, epinephrine and glucose and insulin on hepatic uptake of nonesterified fatty acids.禁食、肾上腺素、葡萄糖及胰岛素对肝脏摄取非酯化脂肪酸的影响。
Am J Physiol. 1960 Sep;199:403-6. doi: 10.1152/ajplegacy.1960.199.3.403.

引用本文的文献

1
EFFECT OF OBESITY AND OF STARVATION ON INSULIN ACTIVITY.肥胖与饥饿对胰岛素活性的影响。
Br Med J. 1965 May 1;1(5443):1153-6. doi: 10.1136/bmj.1.5443.1153.
2
THE ACTION OF INSULIN IN MAN IN THE POSTABSORPTIVE AND POSTPRANDIAL STATES WITH A NOTE ON SOME APPLICATIONS OF ITS ACTION IN DETERMINING MUSCLE FUEL IN MAN.胰岛素在人体吸收后和餐后状态下的作用，并附注其作用在测定人体肌肉燃料方面的一些应用。
Postgrad Med J. 1965 Feb;41(472):67-72. doi: 10.1136/pgmj.41.472.67.
3
EFFECT OF HUMAN GROWTH HORMONE ON MUSCLE AND ADIPOSE TISSUE METABOLISM IN THE FOREARM OF MAN.人生长激素对人体前臂肌肉和脂肪组织代谢的影响。
J Clin Invest. 1965 Jan;44(1):51-61. doi: 10.1172/JCI105126.
4
EFFECT OF VERY SMALL CONCENTRATIONS OF INSULIN ON FOREARM METABOLISM. PERSISTENCE OF ITS ACTION ON POTASSIUM AND FREE FATTY ACIDS WITHOUT ITS EFFECT ON GLUCOSE.极低浓度胰岛素对前臂代谢的影响。其对钾和游离脂肪酸的作用持续存在，而对葡萄糖无作用。
J Clin Invest. 1964 May;43(5):950-62. doi: 10.1172/JCI104981.
5
Hormonal and metabolic changes in starving obese patients during exhaustive physical exercise.
J Endocrinol Invest. 1983 Dec;6(6):445-53. doi: 10.1007/BF03348344.
6
[Inhibition of the effects of insulin by free fatty acids in dogs].[游离脂肪酸对犬胰岛素作用的抑制]
Klin Wochenschr. 1965 Jul 1;43(13):729-32. doi: 10.1007/BF01707071.
7
O2 consumption and metabolite balance in the dog gastrocnemius at rest and during exercise.
Pflugers Arch. 1969;309(1):38-47. doi: 10.1007/BF00592280.
8
The effect of dietary sucrose on blood lipids, serum insulin, platelet adhesiveness and body weight in human volunteers.膳食蔗糖对人类志愿者血脂、血清胰岛素、血小板黏附性及体重的影响。
Postgrad Med J. 1969 Sep;45(527):602-7. doi: 10.1136/pgmj.45.527.602.
9
[Lipid metabolism in the human endometrium and its feto-maternal relationships. Also a discussion on the possible origin of fetal malformations].[人类子宫内膜中的脂质代谢及其母胎关系。同时对胎儿畸形的可能起源进行讨论]
Arch Gynakol. 1968;206(2):107-30. doi: 10.1007/BF00666919.
10
[Lipid metabolism during birth].[出生时的脂质代谢]
Arch Gynakol. 1970 Mar 11;208(3):203-14. doi: 10.1007/BF00666903.

本文引用的文献

1
THEORY OF THE USE OF ARTERIOVENOUS CONCENTRATION DIFFERENCES FOR MEASURING METABOLISM IN STEADY AND NON-STEADY STATES.利用动静脉浓度差测量稳态和非稳态代谢的理论
J Clin Invest. 1961 Dec;40(12):2111-25. doi: 10.1172/JCI104437.
2
Heterogeneity of forearm metabolism with special reference to free fatty acids.前臂代谢的异质性，特别涉及游离脂肪酸。
J Clin Invest. 1962 Jan;41(1):116-25. doi: 10.1172/JCI104453.
3
Effect of insulin on carbohydrate metabolism and on potassium in the forearm of man.胰岛素对人体前臂碳水化合物代谢及钾的影响。
J Clin Invest. 1962 Jan;41(1):108-15. doi: 10.1172/JCI104452.
4
Effects of insulin on glucose and palmitate metabolism by resting and stimulated rat diaphragms.胰岛素对静息和刺激状态下大鼠膈肌葡萄糖及棕榈酸代谢的影响。
Am J Physiol. 1960 Apr;198:807-10. doi: 10.1152/ajplegacy.1960.198.4.807.
5
The effect of insulin on nonesterified fatty acid release from the human leg.胰岛素对人体腿部非酯化脂肪酸释放的影响。
J Clin Invest. 1959 Dec;38(12):2131-4. doi: 10.1172/JCI103991.
6
Observations on the peripheral metabolism of nonesterified fatty acids.关于非酯化脂肪酸外周代谢的观察
Diabetes. 1959 Nov-Dec;8:450-4. doi: 10.2337/diab.8.6.450.
7
Studies on rat adipose tissue in vitro. V. Effects of glucose and insulin on the metabolism of palmitate-1-C14.大鼠脂肪组织的体外研究。V. 葡萄糖和胰岛素对棕榈酸-1-C14代谢的影响。
J Biol Chem. 1960 Feb;235:333-6.
8
Factors influencing the rates of long-chain fatty acid oxidation and synthesis in mammalian systems.影响哺乳动物系统中长链脂肪酸氧化和合成速率的因素。
Physiol Rev. 1961 Jan;41:52-129. doi: 10.1152/physrev.1961.41.1.52.
9
The characteristics of the peripheral transport of C14-labeled palmitic acid.C14标记的棕榈酸外周转运的特征
J Clin Invest. 1960 Oct;39(10):1511-5. doi: 10.1172/JCI104170.
10
Plasma free fatty acid turnover during insulin-induced hypoglycemia.胰岛素诱导的低血糖期间血浆游离脂肪酸周转率
Am J Physiol. 1961 Sep;201:535-9. doi: 10.1152/ajplegacy.1961.201.3.535.

Role of free fatty acids in forearm metabolism in man, quantitated by use of insulin.

作者信息

RABINOWITZ D, ZIERLER K L

出版信息

J Clin Invest. 1962 Dec;41(12):2191-7. doi: 10.1172/JCI104678.

DOI:10.1172/JCI104678
PMID:13972876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC291154/
Abstract
摘要