SIMON E M, STAHL K L, WILSON J B
Appl Microbiol. 1963 Jul;11(4):371-6. doi: 10.1128/am.11.4.371-376.1963.
Differences in the ability to withstand freeze-drying were demonstrated among strains of Salmonella typhimurium. On the average, the number of viable cells in freeze-dried cultures stored at 5 C for 12 to 18 months was approximately one half as large as that found 24 hr after freeze-drying. The viability in samples stored at higher temperatures declined rapidly and was correlated with the dryness of the sample. The virulence for mice of three strains of S. typhimurium did not change appreciably when samples were kept for 1 or 2 years as freeze-dried samples stored at 5 C, or as agar cultures stored at 5 C or at room temperature.
鼠伤寒沙门氏菌不同菌株在承受冷冻干燥的能力上存在差异。平均而言，在5℃下储存12至18个月的冷冻干燥培养物中的活细胞数量大约是冷冻干燥后24小时时发现数量的一半。在较高温度下储存的样品中的活力迅速下降，并且与样品的干燥程度相关。当样品作为在5℃下储存的冷冻干燥样品或作为在5℃或室温下储存的琼脂培养物保存1或2年时，三株鼠伤寒沙门氏菌对小鼠的毒力没有明显变化。
