SZENT-GYORGYI A, HEGYELI A, McLAUGHLIN J A
Science. 1963 Jun 28;140(3574):1391-2. doi: 10.1126/science.140.3574.1391.
Two substances, one promoting growth (promine) of ascites tumors in mice and the other inhibiting it (retine) have both been found in several tissues, namely, thymus, aorta, muscle, and tendon. In spite of similar solubilities in the solvents used for their extraction, the substances could be roughly separated. The value of the ratio between these substances in the same tissue may be significant.
在胸腺、主动脉、肌肉和肌腱等几种组织中都发现了两种物质,一种促进小鼠腹水瘤生长(促瘤素),另一种抑制其生长(抑瘤素)。尽管它们在用于提取的溶剂中的溶解度相似,但这两种物质仍可大致分离。同一组织中这些物质之间的比例值可能具有重要意义。