Paolucci M, Di Fiore M M, Ciarcia G, Botte V
Dipartimento di Zoologia, Università di Napoli, Italy.
Gen Comp Endocrinol. 1992 Aug;87(2):232-9. doi: 10.1016/0016-6480(92)90027-h.
In male Podarcis s. sicula plasma, a sex steroid binding protein [SSBP(s)] binds testosterone (T) and estradiol-17 beta (E2) with moderate affinity (Kd = 0.23 +/- 0.08 x 10(-8) for 3H-E2, and 0.24 +/- 0.07 x 10(-8) for 3H-T) and high capacity. The SSBP binding affinity is unchanged throughout the sexual cycle, although its capacity is higher in nonreproductive males (winter and postreproductive period). This change may be related to changes in plasma T and E2 levels, and is likely to be involved in mechanisms whereby free steroid is delivered to target organs. SSBP, under isoelectrofocusing, is distributed between pH 5.5-6.5 and pH 7.1-7.5. The concentration of these two forms varies during the annual cycle.
在雄性意大利壁蜥血浆中，一种性类固醇结合蛋白[SSBP(s)]以中等亲和力（3H-E2的Kd = 0.23±0.08×10⁻⁸，3H-T的Kd = 0.24±0.07×10⁻⁸）和高结合容量结合睾酮（T）和雌二醇-17β（E2）。尽管在非繁殖期雄性（冬季和繁殖后期）其结合容量较高，但在整个性周期中，SSBP的结合亲和力保持不变。这种变化可能与血浆T和E2水平的变化有关，并且可能参与了将游离类固醇输送到靶器官的机制。在等电聚焦条件下，SSBP分布在pH 5.5 - 6.5和pH 7.1 - 7.
