产生细胞毒性坏死因子CNF1和CNF2的大肠杆菌菌株血清型

Serogroups of Escherichia coli strains producing cytotoxic necrotizing factors CNF1 and CNF2.

作者信息

Blanco J, Blanco M, Alonso M P, Blanco J E, Garabal J I, González E A

机构信息

Departamento de Microbioloxía e Parasitoloxía, Facultade de Veterinaria, Universidade de Santiago, Lugo, Spain.

出版信息

FEMS Microbiol Lett. 1992 Sep 15;75(2-3):155-9. doi: 10.1016/0378-1097(92)90396-6.

DOI:10.1016/0378-1097(92)90396-6

PMID:1398031

Abstract

The serogroups of 396 necrotizing Escherichia coli of human and bovine origin isolated in Spain between 1979 and 1991 have been determined. The 270 cytotoxic necrotizing factor strains belonged to 22 different O serogroups; however, 84% (226 of 270) were of one of seven serogroups (O2, O4, O6, O14, O22, O75 and O83). Although necrotizing E. coli producing cytotoxic necrotizing factor 2 belonged to 28 different serogroups, only six of them (O1, O3, O15, O55, O88 and O123) accounted for 60% (76 of 126) of cytotoxic necrotizing factor 2 strains. Furthermore, only 3% (4 of 126) of cytotoxic necrotizing factor 2 strains belonged to serogroups most common among strains producing cytotoxic necrotizing factor 1. The majority of necrotizing E. coli producing cytotoxic necrotizing factor 1 were obtained from human extraintestinal infections, whereas cytotoxic necrotizing factor 2 strains were isolated from stools of healthy and diarrhoeic calves.

摘要

已测定了1979年至1991年间在西班牙分离出的396株源自人和牛的坏死性大肠杆菌的血清群。270株细胞毒素坏死因子菌株属于22个不同的O血清群；然而，84%（270株中的226株）属于七个血清群（O2、O4、O6、O14、O22、O75和O83）之一。虽然产生细胞毒素坏死因子2的坏死性大肠杆菌属于28个不同的血清群，但其中只有六个（O1、O3、O15、O55、O88和O123）占细胞毒素坏死因子2菌株的60%（126株中的76株）。此外，细胞毒素坏死因子2菌株中只有3%（126株中的4株）属于产生细胞毒素坏死因子1的菌株中最常见的血清群。大多数产生细胞毒素坏死因子1的坏死性大肠杆菌来自人类肠道外感染，而细胞毒素坏死因子2菌株则从健康和腹泻小牛的粪便中分离得到。