编码欧洲伯氏疏螺旋体分离株（B29）两种主要外膜蛋白的完整osp操纵子序列。

Sequence of the complete osp operon encoding two major outer membrane proteins of a European Borrelia burgdorferi isolate (B29).

作者信息

Fellinger W, Redl B, Stöffler G

机构信息

Institut für Mikrobiologie (Med. Fak.), Universität Innsbruck, Austria.

出版信息

Gene. 1992 Oct 12;120(1):127-8. doi: 10.1016/0378-1119(92)90021-g.

DOI:10.1016/0378-1119(92)90021-g

PMID:1398118

Abstract

The nucleotide sequence of the operon encoding the major outer surface proteins, OspA and OspB, of a European isolate of Borrelia burgdorferi (strain B29) was determined and compared to the osp operon of the American strain, B31. An amino acid (aa) identity of 80.7% was found when comparing the OspA of B29 with that of B31, whereas the aa sequence of the OspB of B29 reveals only 61.3% identity with the OspB of B31. Thus, strains B31 and B29 can be regarded as representatives of different B. burgdorferi groups.

摘要

测定了欧洲疏螺旋体伯氏疏螺旋体分离株（菌株B29）编码主要外表面蛋白OspA和OspB的操纵子的核苷酸序列，并与美国菌株B31的osp操纵子进行了比较。将B29的OspA与B31的OspA进行比较时，发现氨基酸（aa）同一性为80.7%，而B29的OspB的aa序列与B31的OspB的同一性仅为61.3%。因此，菌株B31和B29可被视为不同伯氏疏螺旋体组的代表。