伯氏疏螺旋体主要外表面蛋白表达的调控
Regulation of expression of major outer surface proteins in Borrelia burgdorferi.
作者信息
Margolis N, Rosa P A
机构信息
Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840.
出版信息
Infect Immun. 1993 May;61(5):2207-10. doi: 10.1128/iai.61.5.2207-2210.1993.
Abstract
We have characterized a Borrelia burgdorferi clone (CA-11 2A) that does not synthesize the major outer surface proteins, OspA and OspB. While the osp operon is intact and capable of expression, no mRNA transcript is detectable in this clone. These results suggest that osp operon expression in the B. burgdorferi clone can be regulated at the level of transcription.
摘要
我们鉴定了一种伯氏疏螺旋体克隆（CA-11 2A），该克隆不合成主要外表面蛋白OspA和OspB。虽然osp操纵子完整且能够表达，但在该克隆中未检测到mRNA转录本。这些结果表明，伯氏疏螺旋体克隆中osp操纵子的表达可在转录水平上受到调控。
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