Figueroa Damian R, Arredondo Garcia J L
Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología, México, D.F.
Ginecol Obstet Mex. 1992 Aug;60:209-16.
The prevalence of tuberculosis (TB) in Mexico as in the rest of the developing countries is high and no reduction has been noted in the past years. This article describe the clinical features of the disease during the gestational period. We studied 15 cases of TB and pregnancy treated at the Infectious Diseases Department of the Instituto Nacional de Perinatología, from January 1990 to June 1991. At our Institute the incidence was 1.54 cases by 1000 obstetric patients discharged, with a lethality rate of 6.6 deaths by 100 infected patients. We treated 15 women, nine had pulmonary TB, three renal TB, two TB of the cervical lymph node and one cutaneous TB. In seven patients the diagnosis was made before pregnancy, other seven were diagnosed during gestation, and one during puerperium. All patients were treated with antituberculous drugs; the most frequent combination was isoniazid, ethambutol and rifampin. Twelve women had no complications, one died, another developed preeclampsia, and in one case the patient had a low birth weight neonate. No cases of congenital TB were identified and none of the neonates had abnormalities at birth.
与其他发展中国家一样，墨西哥的结核病（TB）患病率很高，且在过去几年中未见下降。本文描述了妊娠期该疾病的临床特征。我们研究了1990年1月至1991年6月期间在国立围产医学研究所传染病科治疗的15例结核病合并妊娠病例。在我们研究所，每1000名出院产科患者中的发病率为1.54例，每100名感染患者中的致死率为6.6例死亡。我们治疗了15名女性，其中9例为肺结核，3例为肾结核，2例为颈淋巴结结核，1例为皮肤结核。7例患者在妊娠前确诊，7例在妊娠期确诊，1例在产褥期确诊。所有患者均接受抗结核药物治疗；最常用的联合用药是异烟肼、乙胺丁醇和利福平。12名女性无并发症，1例死亡，另1例发生先兆子痫，1例患者产下低体重新生儿。未发现先天性结核病病例，且新生儿出生时均无异常。
