Govaerts A, Delespesse G, Duchateau J
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):95-6.
In vitro stimulation of peripheral blood lymphocytes by T mitogens and in MLC is reduced in aging. As the number of T lymphocytes and their antigenic power are in the normal range, a functional T-cell defect is anticipated in high age.
衰老过程中,T 有丝分裂原对外周血淋巴细胞的体外刺激以及混合淋巴细胞培养反应均降低。由于 T 淋巴细胞数量及其抗原活性处于正常范围,预计高龄时会出现功能性 T 细胞缺陷。