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采用C1q沉淀素试验对荨麻疹和急性血清病的研究。

Studies of urticaria and acute serum sickness with the C1q precipitin test.

作者信息

Lieberman P, Rice M C, Mallette J E

出版信息

Arch Intern Med. 1977 Apr;137(4):440-2.

PMID:139855
Abstract

The C1q precipitin test was performed in serum samples from five groups of patients: (1) 20 patients with acomplementemic systemic lupus erythematosus glomerulonephritis (SLE), (2) 2 patients with serum sickness due to the administration of horse serum, (3) 2 patients with serum sickness preceding hepatitis B, (4) 50 patients with chronic urticaria, and (5) 30 normal controls. Positive C1q precipitin tests were found in all patients with SLE and the four cases of serum sickness. Positive tests correlated with depressed serum complement (C3 and C4) levels and were found only in the early phase of serum sickness. Urticaria patients uniformly had negative C1q precipitin tests and normal serum complement levels.

摘要

对五组患者的血清样本进行了C1q沉淀试验:(1)20例患有补体缺乏的系统性红斑狼疮性肾小球肾炎(SLE)的患者;(2)2例因注射马血清而患血清病的患者;(3)2例在乙型肝炎之前患血清病的患者;(4)50例慢性荨麻疹患者;(5)30名正常对照者。在所有SLE患者和4例血清病患者中均发现C1q沉淀试验呈阳性。阳性试验与血清补体(C3和C4)水平降低相关,且仅在血清病的早期阶段出现。荨麻疹患者的C1q沉淀试验均为阴性,血清补体水平正常。

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引用本文的文献

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Studies on circulating immune complexes of the liver diseases. 5. Anti-DNA antibodies and C1q binding activity.肝脏疾病循环免疫复合物的研究。5. 抗DNA抗体与C1q结合活性
Gastroenterol Jpn. 1980 Apr;15(2):167-172. doi: 10.1007/BF02774932.
2
Studies on circulating immune complexes of the liver disease. 4. Clq binding activity.肝脏疾病循环免疫复合物的研究。4. Clq结合活性。
Gastroenterol Jpn. 1980;15(1):27-32. doi: 10.1007/BF02773701.
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Human serum sickness.人类血清病
Clin Rev Allergy. 1985 Feb;3(1):117-26. doi: 10.1007/BF02993045.
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Studies on circulating soluble immune complexes of the liver disease. 1. Inhibition assay of polyclonal rheumatoid factor binding to IgG-sepharose.肝脏疾病循环可溶性免疫复合物的研究。1. 多克隆类风湿因子与IgG琼脂糖结合的抑制试验。
Gastroenterol Jpn. 1979 Dec;14(6):611-6. doi: 10.1007/BF02773720.