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近亲繁殖对生殖结局的影响:基于印度安得拉邦科勒鲁湖内婚制瓦德部落大量样本的研究

Inbreeding effects on reproductive outcome: a study based on a large sample from the endogamous Vadde of Kolleru Lake, Andhra Pradesh, India.

作者信息

Reddy B M

机构信息

Anthropometry and Human Genetics Unit, Indian Statistical Institute, Calcutta.

出版信息

Hum Biol. 1992 Oct;64(5):659-82.

PMID:1398609
Abstract

Inbreeding effects on reproductive outcome vis-à-vis fertility, prenatal loss and prereproductive mortality, and secondary sex ratio of live and dead children were examined in a large sample of 2078 women of the Vadde fishing population of Kolleru Lake in Andhra Pradesh, India. Demographically, this population is a single endogamous unit. By using an exponential regression model with the proportion of offspring survival as a dependent variable and the inbreeding coefficient as an independent variable, I further examined the inbreeding effects. The results were compared with results from other fishing groups and other southern Indian and non-Indian populations. The results among the Vadde were consistent with those found for other groups of Telugu-speaking fishermen and several other southern Indian populations in that the effects were neither perceptible nor significant. The average B value and the number of lethal equivalents found for the highly inbred southern Indian populations in general and for the Vadde in particular were much smaller than those from other parts of the world, providing empirical support to Sanghvi's hypothesis on long-term effects of inbreeding.

摘要

在印度安得拉邦科勒鲁湖瓦德德捕鱼人群的2078名女性的大样本中,研究了近亲繁殖对生殖结果的影响,包括生育力、产前损失和生殖前死亡率,以及活产和死产儿童的出生性别比。从人口统计学角度来看,这个群体是一个单一的族内通婚单位。通过使用以后代存活率比例为因变量、近亲繁殖系数为自变量的指数回归模型,我进一步研究了近亲繁殖的影响。将结果与其他捕鱼群体以及其他印度南部和非印度人群的结果进行了比较。瓦德德人群的结果与其他说泰卢固语的渔民群体以及其他几个印度南部人群的结果一致,即这些影响既不明显也不显著。一般来说,高度近亲繁殖的印度南部人群,特别是瓦德德人群的平均B值和致死当量数远低于世界其他地区,为桑格维关于近亲繁殖长期影响的假设提供了实证支持。

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