Kuwano H, Hashizume M, Yang Y, Kholoussy A M, Matsumoto T
Department of Surgery, Hahnemann University, School of Medicine, Philadelphia, Pennsylvania.
Int Surg. 1992 Jul-Sep;77(3):186-9.
Histological and immunohistochemical studies of the healing processes of expanded polytetrafluoroethylene (PTFE) vascular graft were performed. In the animal experiment, endothelial cell lining, confirmed by immunohistochemical staining for anti-Factor VIII related antigen, existed nearly over all of the pannus. The endothelial cells also formed to some extent over the graft without pannus. Endothelialization showed a close dependency on the surface condition of the underlying tissue rather than on a time factor. In the human experiment, an endothelial island was observed in the middle portion of the graft in one case, supporting the hypothesis of the blood stream origin of endothelial cells.
对膨体聚四氟乙烯（PTFE）血管移植物愈合过程进行了组织学和免疫组织化学研究。在动物实验中，通过抗VIII因子相关抗原免疫组织化学染色证实，几乎在所有血管翳上均存在内皮细胞衬里。在无血管翳的移植物上也有一定程度的内皮细胞形成。内皮化显示出对下层组织表面状况的密切依赖性，而非时间因素。在人体实验中，1例患者的移植物中部观察到内皮岛，支持了内皮细胞来源于血流的假说。
