Angerer J, Hörsch B
Institut für Arbeits- und Sozialmedizin, Universität Erlangen-Nürnberg, Germany.
J Chromatogr. 1992 Sep 16;580(1-2):229-55. doi: 10.1016/0378-4347(92)80537-z.
Methods for the biological monitoring of aromatic hydrocarbons and their metabolites in the human blood and urine are reviewed. For the determination of the unchanged aromatic hydrocarbon in blood, gas chromatographic head-space analysis is recommended. The metabolites can be monitored by photometric, thin-layer chromatographic, high-performance liquid chromatographic and gas chromatographic methods. For the assessment of health risks caused by aromatic hydrocarbons, reference values and occupational limit values, expressed as biological tolerance values and biological exposure indices, have to be considered.
本文综述了人体血液和尿液中芳香烃及其代谢产物的生物监测方法。对于血液中未变化的芳香烃的测定，推荐采用气相色谱顶空分析法。代谢产物可通过光度法、薄层色谱法、高效液相色谱法和气相色谱法进行监测。为评估芳香烃所致的健康风险，必须考虑以生物耐受值和生物暴露指数表示的参考值和职业限值。
