用于测定体液中麦角酸二乙酰胺（LSD）及其代谢物的色谱和质谱方法。
Chromatographic and mass spectrometric methods for determination of lysergic acid diethylamide (LSD) and metabolites in body fluids.
作者信息
Nelson C C, Foltz R L
机构信息
Northwest Toxicology, Inc., Salt Lake City, UT 84124-9906.
出版信息
J Chromatogr. 1992 Sep 16;580(1-2):97-109. doi: 10.1016/0378-4347(92)80530-4.
PMID:1400834
Abstract
Continued illicit use of the potent psychedelic drug lysergic acid diethylamide (LSD) has stimulated efforts to develop effective analytical methods for detection of the drug and its metabolites in body fluids from suspected LSD users. Recently reported methods based on gas and liquid chromatography, combined with single- and multiple-stage mass spectral analysis, now permit accurate detection and quantitation of LSD at sub-nanogram/milliliter concentrations.
摘要
强力迷幻药麦角酸二乙酰胺（LSD）的持续非法使用促使人们努力开发有效的分析方法，以检测疑似LSD使用者体液中的该药物及其代谢物。最近报道的基于气相色谱和液相色谱，并结合单级和多级质谱分析的方法，现在能够在亚纳克/毫升浓度下准确检测和定量LSD。
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