希林试验在原发性吸收不良疾病及部分胃切除术后的可靠性和可重复性。
The reliability and reproducibility of the Schilling test in primary malabsorptive disease and after partial gastrectomy.
作者信息
ADAMS J F, CARTWRIGHT E J
出版信息
Gut. 1963 Mar;4(1):32-6. doi: 10.1136/gut.4.1.32.
A study of the reproducibility and reliability of the Schilling test in patients with primary malabsorptive disease and after partial gastrectomy is reported. The value of the test was assessed by repeated tests in each patient. Consistently normal or abnormal results were obtained in only one of the seven patients with primary malabsorptive disease and in only two of the eight patients who had undergone partial gastrectomy. From these results it is concluded that the result of a single test may be of little clinical value. Assessment of the results suggests that the mean value for a series of Schilling tests may give some indication of value clinically about the capacity to absorb radioactive vitamin B(12) at the time of the tests at least in patients who have undergone partial gastrectomy. The significance of the findings is discussed, particularly in relation to the aetiology of post-gastrectomy megaloblastic anaemia.
本文报告了一项关于希林试验在原发性吸收不良疾病患者及部分胃切除术后患者中的可重复性和可靠性的研究。通过对每位患者进行重复试验来评估该试验的价值。在7例原发性吸收不良疾病患者中，只有1例的多次试验结果始终正常或异常；在8例接受部分胃切除术的患者中，也只有2例如此。从这些结果可以得出结论，单次试验的结果可能临床价值不大。对结果的评估表明，一系列希林试验的平均值至少在接受部分胃切除术的患者中，可能在临床上对测试时吸收放射性维生素B12的能力给出一些有价值的指示。文中讨论了这些发现的意义，特别是与胃切除术后巨幼细胞贫血的病因学相关的意义。
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