Hardten D R, Wen D Y, Wirtschafter J D, Sung J H, Erickson D L
Department of Ophthalmology, University of Minnesota Hospital and Clinics, Minneapolis 55455.
J Clin Neuroophthalmol. 1992 Sep;12(3):158-62.
Optic nervehead swelling is most frequently caused by ocular or intracranial lesions. The case presented here demonstrates that the spinal subarachnoid space must also be considered as a potential site for a lesion causing optic nervehead swelling. A 56-year-old man is presented with an intraspinal lumbar paraganglioma associated with increased cerebrospinal fluid protein, papilledema, transient obscurations of vision, and back pain. This may be the first reported case of a paraganglioma associated with optic nervehead swelling. Magnetic resonance imaging of the lumbosacral region revealed the lesion noninvasively. The papilledema, transient obscurations of vision, and back pain resolved after resection of the tumor. The mechanisms are not defined for optic nervehead swelling in association with spinal tumors in general and paraganglioma in particular. The measured abnormal elevation of cerebrospinal fluid protein may have resulted in increased intracranial pressure and papilledema.
视神经乳头水肿最常见的原因是眼部或颅内病变。本文介绍的病例表明,脊髓蛛网膜下腔也必须被视为导致视神经乳头水肿的病变潜在部位。一名56岁男性患有脊髓腰椎副神经节瘤,伴有脑脊液蛋白升高、视乳头水肿、短暂性视力模糊和背痛。这可能是首例报道的与视神经乳头水肿相关的副神经节瘤病例。腰骶部磁共振成像无创地显示了病变。肿瘤切除后,视乳头水肿、短暂性视力模糊和背痛消失。一般而言,与脊髓肿瘤尤其是副神经节瘤相关的视神经乳头水肿的机制尚不清楚。所测得的脑脊液蛋白异常升高可能导致颅内压升高和视乳头水肿。