McClure D, Lai L C, Cornell C
Department of Clinical Biochemistry, Freeman Hospital, Newcastle upon Tyne.
J Clin Pathol. 1992 Aug;45(8):731-2. doi: 10.1136/jcp.45.8.731.
The phosphate concentrations were measured in 41 patients who had multiple myeloma with paraproteinaemia using four different methods to compare the incidence of pseudohyperphosphataemia. The direct acid/molybdate method produced the highest number of anomalous results. The erroneously high phosphate concentration was attributable to the presence of turbidity in the reaction mixture. No association was found between paraprotein type and occurrence of turbidity. The direct acid/molybdate method was unreliable in patients with serum paraproteins and should therefore not be used for the measurement of phosphate concentration in such patients.
采用四种不同方法对41例伴有副蛋白血症的多发性骨髓瘤患者的磷酸盐浓度进行测量，以比较假性高磷酸盐血症的发生率。直接酸/钼酸盐法产生的异常结果数量最多。磷酸盐浓度错误地升高归因于反应混合物中存在浊度。未发现副蛋白类型与浊度发生之间存在关联。直接酸/钼酸盐法在血清副蛋白患者中不可靠，因此不应使用该方法测量此类患者的磷酸盐浓度。
