Prager P J, Krause K H, Ritz E, Schmidt-Gayk H
Rofo. 1977 Apr;126(4):371-5. doi: 10.1055/s-0029-1230597.
An investigation with 114 epileptic patients under continuous treatment with anticonvulsiva was conducted in order to determine to what extent studies of the handskeleton with low-KV-technique will contribute to diagnosing osteopathy. The roentgenological findings of the hand were correlated with the x-ray findings of the remainder of the skeleton and with the results of biochemical studies. A control biopsy was performed in 8 cases. Definite and with all methods recognizable signs of osteomalacia were present in 7% of the cases, although only 2 patients developed a pathologic fracture. Another 32 patients (28%) showed suspicious changes in the handskeleton, which could not be confirmed by the comparative studies. No patient with normal findings of the handskeleton showed suspicious changes in the remainder of the skeleton or clinical and chemical indications of osteomalacia.
对114名正在接受抗惊厥药持续治疗的癫痫患者进行了一项调查，以确定采用低千伏技术对手骨骼进行的研究在多大程度上有助于诊断骨病。手部的X线检查结果与骨骼其他部位的X线检查结果以及生化研究结果相关联。对8例患者进行了对照活检。7%的病例出现了明确的、用所有方法均可识别的骨软化迹象，尽管只有2例患者发生了病理性骨折。另外32例患者（28%）手部骨骼出现可疑变化，但比较研究未能证实。手部骨骼检查结果正常的患者，其骨骼其他部位均未出现可疑变化，也没有骨软化的临床和化学指征。
