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[胸腺瘤放疗9年后放射性骨髓炎1例报告]

[A case report of radiation osteomyelitis 9 years after irradiation for thymoma].

作者信息

Ohkubo K, Itoi K, Yanagihara K, Matsuoka K, Kuwabara M

机构信息

Department of Chest Disease and Thoracic Surgery, Kansai Denryoku Hospital, Osaka, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1992 Aug;40(8):1233-7.

PMID:1402166
Abstract

Radiation osteomyelitis of the sternum is rare and usually difficult to cure. A 75-year-old man, who had undergone an exploratory sternotomy for a mediastinal tumor, not resected after all, 9 years earlier and received radiation therapy successively for the histological diagnosis of malignant thymoma, was admitted to our hospital with the chief complaint of fever and pus discharge of the anterior chest wall. He also suffered from diabetes mellitus. The skin around the fistula was dark-red and atrophic due to irradiation dermatitis and the manubrium was fissured in the midline. Open drainage and two-stage operation of direct closure was tried in vain. This case was treated successfully by resection of necrosed portion of sternum and pectoral muscle flap closure.

摘要

胸骨放射性骨髓炎罕见且通常难以治愈。一名75岁男性,9年前因纵隔肿瘤接受了胸骨切开探查术,但最终未进行切除,随后因恶性胸腺瘤的组织学诊断先后接受了放射治疗,现因发热和前胸壁脓性分泌物为主诉入院。他还患有糖尿病。瘘管周围的皮肤因放射性皮炎呈暗红色且萎缩,胸骨柄在中线处裂开。尝试了开放引流和直接缝合的两阶段手术,但未成功。该病例通过切除胸骨坏死部分并采用胸大肌皮瓣闭合术成功治愈。

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