Sato K, Maeda K, Ichinose Y, Yano T, Hara N, Ohta M
Department of Chest Surgery, National Kyushu Cancer Center, Fukuoka, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1992 Aug;40(8):1291-4.
An operable case of pedunculated localized mesothelioma of the pleura, a 62-year-old male, came to our clinic with chief complaint of chest X-ray abnormal shadow. On suspicion of pleural tumor, resection was performed. The operative findings revealed that the tumor was arising from visceral pleura of S1 + 2 a segment of left upper lobe, and didn't invade into peripheral tissue. The microscopic findings revealed that the tumor was consist of spindle tumor cells and capillary-like lesions, and had high cellularity and many mitosis. The tumor was diagnosed as localized malignant mesothelioma. Immunohistochemical stainings were performed using six monoclonal antibodies, vimentin, CEA, EMA, keratin (AE1, AE3), Leu-M1. Only vimentin reacted with tumor cells.
一名62岁男性,患有可手术切除的带蒂局限性胸膜间皮瘤,因胸部X线检查发现异常阴影为主诉前来我院就诊。怀疑为胸膜肿瘤后,进行了切除术。手术所见显示肿瘤起源于左上叶S1 + 2段的脏层胸膜,未侵犯周围组织。显微镜检查结果显示肿瘤由梭形肿瘤细胞和毛细血管样病变组成,细胞密度高且有许多核分裂象。该肿瘤被诊断为局限性恶性间皮瘤。使用六种单克隆抗体波形蛋白、癌胚抗原、上皮膜抗原、角蛋白(AE1、AE3)、白细胞共同抗原进行免疫组织化学染色。只有波形蛋白与肿瘤细胞发生反应。