DAY R A, SHAH R
Science. 1962 Dec 7;138(3545):1108-9. doi: 10.1126/science.138.3545.1108.
Penicillinase production in strains of bacillus in which such production is constitutive, as well as in strains in which it is inducible, was found to be a function of the type of penicillin to which the organism was exposed. A repressive effect in two constitutive strains was noted. An increase in the level of penicillinase produced by the constitutive strains was noted for some of the penicillins.
在青霉素酶产生为组成型的芽孢杆菌菌株中,以及在青霉素酶产生为诱导型的菌株中,发现青霉素酶的产生是该生物体所接触的青霉素类型的函数。在两个组成型菌株中观察到了抑制作用。对于某些青霉素,组成型菌株产生的青霉素酶水平有所增加。