Spinella A, Gavagnin M, Crispino A, Cimino G, Martinez E, Ortea J, Sodano G
Istituto per la Chimica di Molecole di Interesse Biologico, C.N.R., Arco Felice, Italy.
J Nat Prod. 1992 Jul;55(7):989-93. doi: 10.1021/np50085a027.
Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysia kurodai. The interconversion of delta- and gamma-lactones in the aplykurodin derivatives has been also investigated.
从斑纹海兔（Aplysia fasciata）的身体外部部位分离出了两种具有鱼毒性的内酯，即4-乙酰阿普利库罗定B [1]和阿普利库罗定酮B [2]。通过光谱和化学方法确定了它们的结构，这些结构与先前从黑边海兔（Aplysia kurodai）中分离出的阿普利库罗定B [3]密切相关。此外，还研究了阿普利库罗定衍生物中δ-内酯和γ-内酯的相互转化。
