Oosterhuis W P, Niemeyer M G, Kuijper A F, Zwinderman A H, Breeman A, Ascoop C A, Verzijlbergen F J, van der Wall E E, Pauwels E K
Department of Diagnostic Radiology (Division of Nuclear Medicine), Academic Hospital, Leiden, The Netherlands.
J Nucl Med. 1992 Oct;33(10):1727-31.
The incremental diagnostic yield of exercise 201Tl scintigraphy with visual and quantitative analysis was determined in 191 patients with known or suspected coronary artery disease (CAD). The coronary arteriogram was used as the gold standard. After pre-test clinical and exercise electrocardiographic data were taken into consideration, scintigraphy was found to have additional diagnostic value both in the diagnosis of CAD and of multivessel disease, with quantitative analysis being superior to visual analysis. The impact of 201Tl scintigraphy on the patient's treatment--conservative treatment versus revascularization--was also evaluated. The impact was relatively low, as the decision for revascularization was based primarily on the angiographic result and the severity of the anginal pain. This result reflects only the decision making process used in our clinic and permits no conclusion to be made concerning the possible value of 201Tl scintigraphy in this type of medical decision making process.
对191例已知或疑似冠心病（CAD）患者进行了运动201铊闪烁显像检查，并进行了视觉和定量分析，以确定其增量诊断价值。冠状动脉造影被用作金标准。在考虑了检查前的临床和运动心电图数据后，发现闪烁显像在CAD和多支血管病变的诊断中均具有额外的诊断价值，定量分析优于视觉分析。还评估了201铊闪烁显像对患者治疗（保守治疗与血运重建）的影响。这种影响相对较小，因为血运重建的决定主要基于血管造影结果和心绞痛的严重程度。这一结果仅反映了我们诊所的决策过程，无法就201铊闪烁显像在这类医疗决策过程中的可能价值得出结论。
