Arguedas A, Mohs E
Department of Pediatric Infectious Diseases, National Children's Hospital, San José, Costa Rica.
J Pediatr. 1992 Oct;121(4):569-72. doi: 10.1016/s0022-3476(05)81146-1.
During the beginning of the 1970s, major changes occurred in Costa Rica in the treatment of streptococcal throat infections. Because of poor compliance with regimens using orally administered agents, intramuscular administration of benzathine penicillin was selected as the standard treatment and throat cultures were eliminated as a prerequisite for prescribing antibiotics. A decline in the incidence of rheumatic fever then occurred. We believe that similar health intervention could be applied in other developing countries.
20世纪70年代初，哥斯达黎加在链球菌性咽喉感染的治疗方面发生了重大变化。由于口服药物治疗方案的依从性较差，选择苄星青霉素肌肉注射作为标准治疗方法，并且不再将咽喉培养作为开具抗生素的前提条件。随后风湿热的发病率有所下降。我们认为，类似的健康干预措施可以应用于其他发展中国家。
