Momma N, Ueda J, Ohsawa K
Tohoku College of Pharmacy, Sendai, Japan.
Yakugaku Zasshi. 1992 Apr;112(4):272-5. doi: 10.1248/yakushi1947.112.4_272.
A simple method using ion-pair high-performance liquid chromatography was established for the rapid and precise determination of sennoside A in oriental pharmaceutical decoctions containing Rhei Rhizoma. This method was compared with other two methods, i.e. ion-suppression and phosphate buffer methods. Sennoside A was eluted without interference in this ion-pair method, while the determination of sennoside A was interfered by co-existing components in the other two methods.
建立了一种采用离子对高效液相色谱法快速、准确测定含大黄的中药汤剂中番泻苷A的简便方法。该方法与另外两种方法，即离子抑制法和磷酸盐缓冲液法进行了比较。在这种离子对方法中，番泻苷A的洗脱不受干扰，而在另外两种方法中，番泻苷A的测定受到共存成分的干扰。
