Servít Z, Horák F
Physiol Bohemoslov. 1977(2):139-42.
The antiepileptic effect of dexphenmetrazine (DP) and acetyldexphenmetrazine (ADP) was tested on audiogenic seizures in a 100% susceptible strain of mice. DP had no antiepileptic effect, however, it markedly suppressed the postparoxysmal motor inhibition. ADP had a distinct anticonvulsive effect--it suppressed the convulsive component of the seizure, leaving its running component unaffected. The results are compared with the effect of both drugs on electrographic epileptic phenomena in the turtle brain (Servít and Strejcková 1976).
在100%易患癫痫的小鼠品系中，测试了右苯丙胺（DP）和乙酰右苯丙胺（ADP）对听源性癫痫发作的抗癫痫作用。DP没有抗癫痫作用，然而，它显著抑制了发作后的运动抑制。ADP有明显的抗惊厥作用——它抑制了癫痫发作的惊厥成分，而其奔跑成分未受影响。将这些结果与这两种药物对龟脑电图癫痫现象的作用进行了比较（塞尔维特和斯特雷乔科娃，1976年）。
