Turell M J, Beaman J R
Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702.
J Med Entomol. 1992 Sep;29(5):802-5. doi: 10.1093/jmedent/29.5.802.
Experimental studies were undertaken to ascertain the vector competence of a strain of Aedes albopictus (Skuse) collected in New Orleans, LA, (Gentilly strain) for an epizootic (Trinidad donkey) strain of Venezuelan equine encephalomyelitis (VEE) virus. This strain of Ae. albopictus was significantly more susceptible to infection with VEE virus than were any of the four strains tested previously, including two from North America and two from South America. Likewise, dissemination (148 of 180) (82%) and transmission (40 of 88) (45%) rates were significantly higher in the Gentilly strain than in any of the strains previously tested. Analysis of the results of the present study along with those of a previous study with a second alphavirus, chikungunya (CHIK) virus, indicated that, although all three strains of Ae. albopictus tested were more susceptible to VEE virus than to CHIK virus, susceptibility to infection and dissemination with one alphavirus appeared to be directly related to susceptibility to infection and dissemination with the other virus and may indicate shared receptor sites for these two alphaviruses in Ae. albopictus.
开展了实验研究，以确定在路易斯安那州新奥尔良收集的一株白纹伊蚊（斯库斯）（金蒂利株）对委内瑞拉马脑炎（VEE）病毒的一种动物流行病株（特立尼达驴株）的媒介能力。该株白纹伊蚊对VEE病毒的易感性明显高于之前测试的四种毒株中的任何一种，包括两种来自北美洲和两种来自南美洲的毒株。同样，金蒂利株的传播率（180只中有148只）（82%）和传播率（88只中有40只）（45%）明显高于之前测试的任何毒株。对本研究结果以及之前一项关于另一种甲病毒基孔肯雅（CHIK）病毒的研究结果进行分析表明，尽管测试的所有三株白纹伊蚊对VEE病毒的易感性均高于对CHIK病毒的易感性，但对一种甲病毒的感染和传播易感性似乎与对另一种病毒的感染和传播易感性直接相关，这可能表明这两种甲病毒在白纹伊蚊中存在共同的受体位点。
