Beaman J R, Turell M J
Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702.
J Med Entomol. 1991 Jan;28(1):161-4. doi: 10.1093/jmedent/28.1.161.
Experimental studies were undertaken to ascertain the vector potential of North American (Houston and Alsace) and South American (Sao Paulo and Santa Teresa) strains of Aedes albopictus (Skuse) for an epizootic (Trinidad donkey) strain of Venezuelan equine encephalomyelitis (VEE) virus. Infection rates were similar in all four strains of Ae. albopictus tested after ingestion of VEE virus from a viremic hamster. Virus disseminated from the midgut to the hemocoel in about 80% of infected mosquitoes, regardless of the dose ingested (10(4.6) to 10(5.7) plaque-forming units per mosquito) or the time of extrinsic incubation (7-35 d). Although all four strains of this mosquito transmitted VEE virus by bite to hamsters, transmission rates were significantly higher for the South American strains (24%, 40 of 170) than for the North American strains (5%, 9 of 165). Although VEE virus has never been isolated from Ae. albopictus, the introduction of this species into the Americas may allow it to serve as an amplification vector in areas where epizootic strains of VEE are found or introduced.
开展了实验研究，以确定北美（休斯顿和阿尔萨斯）和南美（圣保罗和圣特雷莎）白纹伊蚊（斯库斯）品系对委内瑞拉马脑炎（VEE）病毒的一种动物流行病（特立尼达驴）毒株的传播潜能。在从感染病毒的仓鼠摄入VEE病毒后，所测试的所有四种白纹伊蚊品系的感染率相似。无论摄入剂量（每只蚊子10(4.6)至10(5.7)个空斑形成单位）或外在潜伏期（7 - 35天）如何，约80%受感染的蚊子体内病毒从中肠扩散至血腔。虽然这种蚊子的所有四个品系都能通过叮咬将VEE病毒传播给仓鼠，但南美品系的传播率（24%，170只中有40只）显著高于北美品系（5%，165只中有9只）。虽然从未从白纹伊蚊中分离出VEE病毒，但该物种引入美洲可能使其在发现或引入VEE动物流行病毒株的地区成为扩增媒介。
